The Effects of Acoustic Interface Layer on Biological Focal Region By High Intensity Focused Ultrasound

摘要

Interface layer was simulated by the magnetic nano-particles in the egg white phantom,and then the high intensity focused ultrasound (HIFU) was introduced to exposure egg white phantom in different depth blowing the acoustic interface by the same dosage using "point" exposure.The results show that the volumes of Biological Focal Region (BFR) enlarge.This means the magnetic nano-particles can enhance the therapeutic efficiency of HIFU when the Acoustic Focal Region (AFR) close with interface layer.When distance of the AFR from the interface layer was 10mm,the size and shape of the BFR were similar with control group,but there was a large lesion at the interface,this was harm for treatment.When distance of the AFR from the interface layer was 30mm,the size and shape of the BFR were similar with control group.When the thickness of the interface layer diminished,the utility of enhancement decreased.