Thermal Damage Control of Dye-Assisted Laser Tissue Welding: Effects of Dye Concentration

摘要

Successful laser-assisted tissue welding was implemented to provide proper weld strength with minimized tissue thermal injury. We investigated and compared the weld strengths and morphologic changes in porcine small intestinal submucosa (SIS) and porcine ureteral tissues with various concentration of indocyanine green (ICG) and with a wolid albumin sheet. The study showed that the tissues were welded at lower ICG concentration (0.05 mM) with minimized tissue thermal damage using an 800-nm wavelength diode laser.