TIME-DELAYED RELEASE OF PARACETAMOL IN MAN FROM THE HYDROPHILIC SANDWICH (HS) CAPSULE

机译：亲水性丹参（HS）胶囊中人中帕拉西坦的时滞释放

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Paracetamol release from a gastroresistant form of the hydrophilic sandwich (HS) capsule designed to target the proximal colon has been investigated in man using salivary analysis. Drug was detected in the saliva from 5.7 hr, with T_(max) determined at 7.9 hr.

机译：使用唾液分析技术已在人体中研究了扑热息痛从亲水性三明治（HS）胶囊的胃耐性形式释放出来的目的，该胶囊旨在靶向近端结肠。从5.7小时开始在唾液中检测到药物，在7.9小时确定T_（max）。

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来源
《International symposium on controlled release of bioactive materials;Consumer diversified products conference》|2001年|p.790-791|共2页
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S. Soutar; B. OMahony; A.C. Perkins; T. Grattan; C.G. Wilson; M. Bakhshaee; H.N.E. Stevens;
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中图分类基础医学;
关键词
HS capsule; gastro-resistant; dissolution; pharmacokinetics; saliva; colon delivery;

机译：HS胶囊;耐胃解散药代动力学唾液;结肠分娩;

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机译：基于溶水层液晶@硬胶囊的智能相变系统，用于持续释放亲水和疏水药物
2. Release of small hydrophilic molecules from polyelectrolyte capsules: Effect of the wall thickness [J] . Cuomo Francesca, Lopez Francesco, Piludu Marco, Journal of Colloid and Interface Science . 2015,第Null期

机译：小亲水分子从聚电解质胶囊中释放：壁厚的影响
3. Robust molecular micro-capsules for encapsulating and releasing hydrophilic contentst [J] . Francisco Vera, Marta Mas-Torrent, Civan Avci, Chemical Communications . 2013,第71期

机译：健壮的分子微胶囊，用于包裹和释放亲水性内容物
4. GAMMA SCINTIGRAPHIC INVESTIGATION OF DRUG RELEASE FROM A TIME-DELAYED CAPSULE [C] . Jason McConville, Bridget OMahony, Blythe Lindsay, Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：延时胶囊对药物释放的伽玛射线谱研究
5. 1. Development of hot-melt pan-coating, application to sustained-release capsules and tamper resistant-coating. 2. Formulation of verapamil hydrogen chloride and diltiazem hydrogen chloride semisolid matrix capsules. 3. Novel sustained release tablet of glipizide: Compression of coated drug beads, formulation, dissolution, and convolution. 4. Verapamil sustained release: New formulation and convolution. [D] . Nguyen, Chien Ngoc. 2006

机译：1.开发热熔性包衣，应用于缓释胶囊和防篡改包衣。 2.配制维拉帕米氯化氢和地尔硫卓氯化氢半固体基质胶囊。 3.格列吡嗪的新型缓释片剂：包衣药物珠的压缩，制剂，溶解和卷积。 4.维拉帕米缓释剂：新配方和卷积剂。
6. Smart phase transformation system based on lyotropic liquid crystalline@hard capsules for sustained release of hydrophilic and hydrophobic drugs [O] . Xuejuan Zhang, Yujun Xiao, Zhengwei Huang, 2020

机译：基于溶致液晶@硬胶囊的智能相变系统用于持续释放亲水性和疏水性药物
7. Robust molecular micro-capsules for encapsulating and releasing hydrophilic contents [O] . Vera, Francisco, Mas-Torrent, Marta, Avci, Civan, 2013

机译：坚固的分子微胶囊，用于包裹和释放亲水性内容物

TIME-DELAYED RELEASE OF PARACETAMOL IN MAN FROM THE HYDROPHILIC SANDWICH (HS) CAPSULE

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