Study Of Intestinal Absorption Of A New Quinolone In Rats

摘要

Many compounds belonging to different categories of drugs have been reported to be actively secreted by intestinal efflux systems as P-glycoprotein (P-gp)~1,2,3. The existence of a intestinal secretion process for some fluorquinolones seem to be demonstrated in biological systems like Caco-2 cells~4,5.