Polysohexylcyanoacrylate nanoparticles efficiently concentrate 3' azido 3' deoxythymidine (AZT) in the gastrointestinal mucosa

机译：聚己二酸氰基丙烯酸酯纳米颗粒可在胃肠道粘膜中有效浓缩3'叠氮基3'脱氧胸苷（AZT）

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

The gastrointestinal tract contains various immuno competent cells which are an important target for the human immunodeficiency virus (HIV) (1). The presence of the virus has been identified in cells of the lamina propria (lymphocytes, macrophages, and dendritic cells) (2), and in M-cells (3). Morevoer, the presence of HIV in enterocytes has been suspected (4).

机译：胃肠道包含各种免疫感受态细胞，它们是人类免疫缺陷病毒（HIV）的重要靶标（1）。已在固有层的细胞（淋巴细胞，巨噬细胞和树突状细胞）（2）和M细胞（3）中鉴定出病毒的存在。此外，怀疑肠细胞中存在HIV（4）。

著录项

来源
《International symposium on controlled release of bioactive materials;Consumer and diversified products conference》|2000年|p.1106-1107|共2页
会议地点
作者
A.Dembri; H.Chacun; D.Duchenen; G.Ponchel;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类基础医学;
关键词

相似文献

外文文献
专利

1. Targeting of 3'-azido 3'-deoxythymidine (AZT)-loaded poly(isohexylcyanoacrylate) nanospheres to the gastrointestinal mucosa and associated lymphoid tissues. [J] . Dembri A, Montisci MJ, Gantier JC, Pharmaceutical research . 2001,第4期

机译：靶向3'-叠氮基3'-脱氧胸苷（AZT）的聚（异己基氰基丙烯酸酯）纳米球靶向胃肠粘膜和相关的淋巴组织。
2. Structural basis for the efficient phosphorylation of AZT-MP (3′-azido-3′-deoxythymidine monophosphate) and dGMP by Plasmodium falciparum type?I thymidylate kinase [J] . Ana?P.?G. Silva, Anthony?J. Wilkinson, Dolores González-Pacanowska, The biochemical journal . 2010,第3期

机译：恶性疟原虫I型胸苷酸激酶对AZT-MP（3'-叠氮基3'-脱氧胸苷单磷酸）和dGMP有效磷酸化的结构基础
3. Structural basis for the efficient phosphorylation of AZT-MP (3 '-azido-3 '-deoxythymidine monophosphate) and dGMP by Plasmodium falciparum type I thymidylate kinase [J] . Whittingham Jean L., Carrero-Lerida Juana, Brannigan James A., The Biochemical Journal . 2010,第3期

机译：恶性疟原虫I型胸苷酸激酶对AZT-MP（3'-叠氮基3'-脱氧胸苷单磷酸）和dGMP有效磷酸化的结构基础
4. Polysohexylcyanoacrylate nanoparticles efficiently concentrate 3' azido 3' deoxythymidine (AZT) in the gastrointestinal mucosa. [C] . A.Dembri, H.Chacun, D.Duchenen, International symposium on controlled release of bioactive materials . 2000

机译：聚己酰氨基丙烯酸酯纳米颗粒有效地浓缩3'氮杂铜3'DoOxythynidine（AZT）在胃肠粘膜中。
5. In vitro and in vivo catabolism of the anti-HIV 2',3'-dideoxynucleoside, 3'-azido-3'-deoxythymidine (AZT). [D] . Cretton, Erika Maya. 1991

机译：抗HIV 2'，3'-双脱氧核苷，3'-叠氮基3'-脱氧胸苷（AZT）的体外和体内分解代谢。
6. 3′-Azido-3′-Deoxythymidine (AZT) and AZT-Resistant Reverse Transcriptase Can Increase the In Vivo Mutation Rate of Human Immunodeficiency Virus Type 1 [O] . Louis M. Mansky, Lisa C. Bernard 2000

机译：3-叠氮基-3-脱氧胸苷（AZT）和抗AZT的逆转录酶可以提高人类免疫缺陷病毒1型的体内突变率。
7. Structural basis for the efficient phosphorylation of AZT-MP (3 '-azido-3 '-deoxythymidine monophosphate) and dGMP by Plasmodium falciparum type I thymidylate kinase [O] . Whittingham, Jean L., Carrero-Lerida, Juana, Brannigan, James A., 2010

机译：恶性疟原虫I型胸苷酸激酶对AZT-MP（3'-叠氮基3'-脱氧胸苷单磷酸）和dGMP有效磷酸化的结构基础
8. NTP Technical Report on the Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), Nevirapine (NVP), and Velfinavir Mesylate (NFV) (CAS NO. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice [R] . 2013

机译：NTp技术报告关于3'-叠氮基-3'-脱氧胸苷（aZT），拉米夫定（3TC），奈韦拉平（NVp）和维美奈韦甲磺酸盐（NFV）混合物的毒理学和癌变研究（Cas NO.30516-87-1），B16C3F1小鼠，134678-17-4,129618-40-2,159989-65-8）

Polysohexylcyanoacrylate nanoparticles efficiently concentrate 3' azido 3' deoxythymidine (AZT) in the gastrointestinal mucosa

摘要

著录项

相似文献

相关主题

期刊订阅