Abstract: Optical biopsy of stomach mucosa was performed afterwards oral administration of encapsulated hyperflav (single dose was chosen to provide 0.1 - 0.15 mg/kg b.w.) A sufficient fluorescence contrast of suspicions versus normal tissue was obtained after incubation time from 4 to 10 hours. Fluorescence was induced by He - Cd laser coupled to fiber optic probe inserted into a biopsy channel of the endoscope. Fluorescent spectra were recorded in the range from 500 nm up to 700 nm with 2 nm resolution. We took two groups of patients with benign and malignant ulcer of the stomach and erosive gastritis. The first group consisted of 59 patients (male/female 36/23) was carried out with optical biopsy of stomach mucosa. The second group consisted of 60 patients (male/female 39/21) was carried out by routine method: gastroscopy and biopsy from 5 - 7 places of macroscopically changed mucosa.!8
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机译：摘要：口服粘膜黄酮（单剂量选择为0.1-0.15 mg / kg b.w.）口服给药后，对胃粘膜进行光学活检。温育时间为4至10小时后，获得了与正常组织充分的荧光对比。 He-Cd激光耦合到插入内窥镜活检通道的光纤探头，诱导荧光。在500 nm至700 nm的范围内以2 nm的分辨率记录了荧光光谱。我们选择了两组患有胃良性和恶性溃疡以及糜烂性胃炎的患者。第一组由59例患者组成（男/女36/23），并进行了胃粘膜的光学活检。第二组由60例患者组成（男/女39/21），采用常规方法进行：胃镜检查和活检，检查范围为5-7个肉眼可见改变的粘膜。8
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