Coherent detection imaging of absorption and scattering in tissues and tissuelike phantoms

摘要

Abstract: This paper presents measurement results of absorption and scattering in tissues and tissuelike phantoms by using coherent detection imaging (CDI) technique. CDI measurements are carried out in 0.8 - 1.3 micrometer wavelength region by using several continuous wave, single frequency lasers, including a tunable Ti:sapphire laser and laser diode-pumped Nd:YAG lasers. A 120 dB dynamic range achieved with less than 10 mW incident power and a detection time of 0.1 msec enables spectroscopic measurements through attenuation of as much as exp($MIN@27). Measurement results using cw lasers are also compared to the temporal scattering profiles of coherent photon migration in highly scattering media. For this purpose, a modified CDI system using low-coherence super luminescent diodes has been developed. The results from the laser and low coherence CDI measurements are found to be consistent. !11