Recursive estimation of lung mechanical parameters in newborn infants during mechanical ventilation

摘要

A single-compartment lung model has been used to describe the dynamic pulmonary mechanical function in seven newborn infants. The subjects had low birth weights, less than 1500 g, and were studied under intermittent positive pressure ventilation. Linear regression techniques were used to calculate two lung model parameters, compliance (C) and resistance (R), for single breaths. The main interest has been to describe how the C and R parameter values vary within single breaths. A recursive linear regression technique was found to detect parameter value changes well.