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The Feynman Propagator to Model Molecular Communications Between an Engineered Nanodevice and Beta Cells

机译:Feynman传播器可对工程纳米器件和Beta细胞之间的分子通信进行建模

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In a prospective scenario of nanomedicine, an engineered cargo of nanoparticles would be crucial to alleviate diseases that might to require of a precise doses of biochemical compounds in situ. In this paper, the technique of Feynman's propagator to estimate the probability amplitude in the different paths of a charged nanoparticle that would opt to reach a beta cell, is employed. The aim is to generate the artificial releasing of granules of insulin in beta cells to avoid hyperglycemia in those diabetes patients. For this end the quantum mechanics evolution operator is employed. Once the square of the amplitudes are calculated, it leads to analyzed the cases in where repulsive electric forces might to cause to decrease the chance of nanoparticle to go through the cell. Computational simulations are presented.
机译:在纳米药物的前瞻性场景中,工程化的纳米颗粒货物对于减轻可能需要就地精确剂量的生化化合物的疾病至关重要。在本文中,采用了费曼传播子技术来估计带电纳米粒子选择到达β细胞的不同路径中的概率振幅。目的是在β细胞中人工释放胰岛素颗粒,以避免那些糖尿病患者出现高血糖。为此,采用了量子力学演化算子。一旦计算了振幅的平方,就可以分析排斥电势可能导致减少纳米粒子通过细胞的机会的情况。提出了计算仿真。

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