Human Amniotic Membrane Enhanced Allograft Bone Graft

摘要

Allogenic bone bioimplants enhanced with human amniotic membrane demonstrated better bone healing than those with allogenic bone alone at 6 weeks in this rabbit critical sized defect model at both femoral and tibial implant sites. When mixed with human amniotic membrane, allogenic bone bioimplants promoted the deposition of more solid bone ossicles than those with allogenic bone alone. Bone bioimplants using allogenic corticocancellous bone chips mixed with human amniotic membrane were shown to be highly effective osseous bone void fillers. Histological processing of the samples and histomorphometric quantitation will be performed to confirm the microCT results.