Reducing Microelectrode Shaft Size and Including a Soft, Permeable Base Coating Improves UEA Biocompatibility

摘要

This study showed that reducing the size of the microelectrode shafts and adding a soft, permeable base coating was sufficient to reduce the neural lesion that accompanies UEA implantation after a 3 month indwelling period without affecting other FBR biomarker distribution. The study results support the notion that continued optimization of existing technology can further improve the biocompatibility of such implants. Future studies will examine whether such changes can also improve long-term recording performance.