Rolled PCL/GelMA Composites as Scaffolds for ACL Repair

摘要

Crosslinked GelMA hydrogels can be created with different mechanical properties, which are expected to affect cell infiltration and proliferation. Storage modulus increases with GelMA concentration, and 30 s of UV irradiation results in moduli of 162-1075 Pa. Longer crosslinking times is expected to increase storage modulus, but may slow cell infiltration. Once a range of GelMA moduli are established that support cell infiltration, rolled composites will be tested in vivo in a rabbit patellar tendon defect.