Methacrylic Acid Based Biomaterials for Peripheral Nerve Regeneration

摘要

MAA-based biomaterials promote an increase in the expression of UCHL1 as well as an increase in PGP9.5 staining. These results suggest that MAA-based biomaterials promote peripheral nerve growth in the subcutaneous space. Future studies will examine the effect of MAA in a peripheral neuropathy model and assess the efficiency in restoring sensory functions. MAA-based biomaterials will address unmet medical needs through the use of regenerative biomaterials to promote endogenous PNI repair.