Data Driven GUI Design and Visualization for a NGS Based Clinical Decision Support System

摘要

Next-generation sequencing (NGS) has transformed genomic research by decreasing the cost of sequencing and increasing the throughput. Today the translation of NGS technology to (cancer) diagnostics and therapeutics is widely anticipated. In this paper we give an overview of design, user experience and usability (DUXU) requirements for NGS applications with a special focus on clinical and diagnostic settings and describe a data driven GUI and visualization framework for a NGS based clinical decision support system (DSS). In such a DSS it is hard to oversee the huge amount of information, especially if given only in textual form. To overcome this we developed a visual language for electronic health records (EHR) for navigation within a case and comparison of medical cases.