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Biocellulose scaffold obtained by in situ modifications with water-soluble cellulose derivative

机译:通过水溶性纤维素衍生物原位修饰获得的生物纤维素支架

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Tissue engineering is to develop alternative methods for tissue regeneration, applicable to degenerative processes, and congenital deformities in progressive disease, among other possibilities. In this scenario, the bacterial cellulose stands out as a promising biopolymer for the preparation of scaffolds and their use in tissue engineering as temporary substituents of injured or damaged tissue.ln this work we have prepared and characterized scaffolds based on biocelluloseby in situ modification by using a water-soluble cellulose derivative, which is, carboxymethylcellulose (CMC). Modified BC scaffolds wew characterized by different physico-chemical tests, namely, Atomic ForceMicroscopy (AFM) and Fourier Transform Infrared Spectroscopy (FTIR).The results revealed additional features bacterial cellulose, such as increased adhesion and deformation and demonstrated the incorporation of the CMC structure effectively cellulose.
机译:组织工程学是为了开发组织再生的替代方法,该方法适用于变性过程和进行性疾病中的先天性畸形。在这种情况下,细菌纤维素是一种有前途的生物聚合物,可用于制备支架及其在组织工程中用作受伤或受损组织的临时取代基。水溶性纤维素衍生物,即羧甲基纤维素(CMC)。改性的BC支架具有不同的理化测试,分别是原子力显微镜(AFM)和傅立叶变换红外光谱(FTIR),其结果显示细菌纤维素具有其他功能,例如增加的粘附力和变形,并证明了CMC结构的整合有效地纤维素。

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