This paper dicusses how to formalize medical diagnostic reasoing from the viewpoint of rule reasoning. Characteristics of rules shows that the rule model is closely related with rough set rule model. The important point is that medical diagnostic reasoning is characterized by focusing mechanism, composed of screening and differential diagnosis, which corresponds to upper approximation and lower approximation of a target concept in rough set theory. Furthremore, this paper focuses on detection of complications, which can be viewed as relations between rules of different diseases.
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