Controlled Release of Simvastatin from Anodized Ti Granules for Improving its Antibacterial Effects

摘要

Therefore loading simvastatin on Ti granules through physical adsorption give a valuable opportunity for improving antibacterial properties of granules. It was concluded that nanowire arrays on favored medical implant materials have a high potential for loading with antimicrobial agents. Although simvastatin loading improve antibacterial properties of G samples more than AG ones but the sustain release of simvastatin in AG samples could result in improving other properties of the granules such as donating osteoanabolic effects which should be investigated in future studies.