Magnetite-doped organic-inorganic nanocomposite scaffolds stimulate bone cell functions

摘要

The MN-incorporated sol-gel processed scaffolds exhibited excellent magnetic properties, preserving the superparamagnetic behavior of native MN. The MN scaffolds showed significantly improved mechanical properties, effective for bone tissue engineering. The MN incorporation increased water uptake and swelling of the scaffolds. The MN addition preserved the excellent apatite-forming ability of the scaffold in SBF. The MSCs cultured on the magnetic scaffolds were significantly promoted in proliferation and osteogenic differentiation, implying usefulness for bone tissue engineering.