Collagen NanoFiber Coating on Cell Surfaces for Construction of Cell-Density Controlled 3D-Thick Tissues

摘要

We demonstrate control of cell density and ECM thickness in 3D-tissue constructs using the collagen matrix coating technique. Moreover, millimeter-sized thick but lower cell density tissues were successfully constructed by this method. It is expected to fabricate complex and functional 3D-tissues for biomedical application.