Antimicrobial Oxygen-Generating Injectable Scaffold for Wound Healing

摘要

Oxygen-generating microparticles and PNIPAM-CS injectable hydrogel were successfully fabricated. The OGIS can be injected and gelled in situ at 37 °C to fill tissue defects and provide a long-term oxygen delivery, enhance cell proliferation under hypoxic wounded environments, while simultaneously against bacterial infection or improve the existing chronic infection conditions. All of the results suggested that the OGIS can be designed and developed as wound healing scaffold.