A wireless implantable drug infusion system with integrated dosing sensors

摘要

A wireless electrolysis-based drug delivery system with integrated electrochemical dosing sensors suitable for management of chronic conditions is presented. Repeatable delivery performance for identical and variable bolus volumes and flow rates of phosphate buffer saline (PBS) was demonstrated. Successful delivery and sensing of 17.75 ± 0.48 µL boluses (1.78% of reservoir fill volume) of lidocaine was achieved.