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Aptasensor for diabetes mellitus detection and monitoring

机译:用于糖尿病检测和监测的Aptasensor

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DNA aptamers against GHSA, which is protein marker for diabetes mellitus, were selected and modified. In combination properties of modified GHSA binding aptamer and fluorescence quenching of GO, we develop simple and sensitive platform for detection of GHSA in both PBS and human serum with the LOD of 50 μg/mL. We envision that our GO-aptamer platform has a potential to be GHSA detection for screening and monitoring diabetes mellitus.
机译:选择和修饰针对GHSA的DNA适体,GHSA是糖尿病的蛋白质标记。结合修饰的GHSA结合适体和GO荧光猝灭的组合特性,我们开发了一种简单而灵敏的平台,可检测PBS和人血清中的GHSA,其LOD为50μg/ mL。我们设想,我们的GO-aptamer平台有可能成为GHSA检测手段,用于筛查和监测糖尿病。

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