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Microchip based ion source powered by a lighter piezo-generator for mass-spectrometry detection

机译:基于Microchip的离子源,由较轻的压电发生器提供动力,用于质谱检测

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This study presents a microchip device powered by a lighter piezo-generator for producing corona discharge for ambient mass-spectrometry (MS) detection. A low-cost lighter piezo-generator is capable of producing a high voltage pulse of 10~12 kV for generating corona discharge. The energetic corona discharge simultaneously desorbs and ionizes the solid samples for mass spectrometry detections. Results shows that the discharge behavior of the lighter piezo-generator is stable enough for producing high voltage pulses and the measured ion intensity is higher than 10 ions/cm. The optical emission spectrum of the discharged glow indicates that helium and oxygen are successfully discharged. Standard sample of caffeine is used to evaluate the sensing performance of the developed ion source. Results indicate that the MS chip powered by the lighter-generator is capable of detecting caffeine of the concentration as low as 10 ppm without delicate sample preparation procedures. In addition, three clinical medicines including a human sex hormone of estradiol, panadol tablet and a typical steroid of clenbuterol are successfully detected using the developed MS chip. The developed MS chip powered by the lighter piezo-generator has demonstrated the possibility for establishing a portable MS detection system.
机译:这项研究提出了一种由较轻的压电发生器提供动力的微芯片设备,该设备可产生用于环境质谱(MS)检测的电晕放电。低成本的轻型压电发电机能够产生10〜12 kV的高压脉冲,以产生电晕放电。高能电晕放电同时使固体样品解吸和离子化,以进行质谱检测。结果表明,较轻的压电发生器的放电行为足够稳定,可以产生高压脉冲,并且测得的离子强度高于10离子/ cm。释放的辉光的光谱发射光谱表明氦和氧已成功释放。咖啡因的标准样品用于评估已开发离子源的传感性能。结果表明,由打火机驱动的MS芯片无需复杂的样品制备程序即可检测浓度低至10 ppm的咖啡因。此外,使用开发的MS芯片成功检测出三种临床药物,其中包括人体雌性激素雌激素,潘那多片和典型的盐酸克仑特罗类固醇。由较轻的压电发生器提供动力的已开发MS芯片已经证明了建立便携式MS检测系统的可能性。

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