Convenient preparation of patterned temperature-responsive cell culture surface by using thioxanthone based photo-initiator modified polystyrene surfaces

摘要

PAAm chains were successfully grafted onto PIPAAm-PSt surface with visible light induced polymerization and grafting method through the photomask. The successful graft of PAAm suggested that remaining radical molecules on PIPAAm-PSt were activated to initiate polymerization by photo irradiation. Namely, block-copolymer containing PIPAAm and PAAm segments and PIPAAm chains were grafted on PSt surface. The PAAm component exhibited protein and cell repellent character. This method is expected to be a convenient method for preparation of TRCS with micro-patterned surface.