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Conducting Polymer Microtubes for Bioactuators

机译:用于生物术递器的聚合物微管

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摘要

Conducting polymer (CP) actuators are promising devices for biomedical applications such as artificial muscles and drug delivery systems. Here, we report a tri-layer actuator based on poly(pyrrole) (PPy) microtubes (PPy MTs) doped with poly(sodium-p-styrenesulfonate) (PSS) and constructed on a passive layer of gold-coated poly-propylene (PP) film. The PPy MTs were fabricated using electrochemical deposition of PPy around poly(lactic-co-glycolic acid) (PLGA) fiber templates, followed by template removal. The PPy MTs were subjected to a redox process using cyclic voltammetry in 0.1 M NaPSS electrolyte solution as the potential was swept between –0.8 V and +0.4 V for 5 cycles at the scan rates of 10, 50, 100, and 200 mV/s. The bending behavior of the PPy MTs actuator was investigated by measuring the deflection of actuator tip resulting from the expansion/contraction strain of PPy MTs. The PPy MTs actuator showed a reversible bending movement during each potential cycle. The maximum deflection of actuator decreased by increasing the scan rate that was confirmed by calculating the actuation strain generated during each cycle at various scan rates.
机译:导电聚合物(CP)致动器是用于生物医学应用的有前途的装置,例如人造肌肉和药物递送系统。这里,我们报告基于聚(吡咯)三层致动器(PPY)的微管(PPY MTS)掺杂有聚(钠 - 对 - 苯乙烯磺酸)(PSS)和构造金涂覆的聚丙烯的无源层(上PP)薄膜。使用围绕聚(乳酸 - 乙醇酸)(PLGA)纤维模板的PPY的电化学沉积来制造PPY MTS,然后进行模板去除。使用0.1μs的循环伏安法在0.1μs的电解质溶液中进行氧化还原方法,因为在扫描速率为10,50,100和200 mV / s的扫描速率下扫描到50.8V和+ 0.4V的电位。 。通过测量由PPY MT的膨胀/收缩菌株产生的致动器尖端的偏转来研究PPY MTS致动器的弯曲行为。 PPY MTS执行器在每个潜在循环期间显示了可逆弯曲运动。致动器的最大偏转通过增加通过计算在各个扫描速率期间在每个循环期间产生的致动应变而确认的扫描速率而降低。

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