Multi-source signal processing in phonocardiography: comparison among signal selection and signal enhancement techniques*

摘要

Phonocardiography (PCG) is a promising tool for the diagnosis and follow-up of cardiovascular diseases. To date it is available only in clinical settings, because it relies on an experienced examiner for the positioning of the electronic stethoscope. Making it possible for an unexperienced user to obtain high quality PCG signals would allow for developing instruments suitable for homecare purposes. In this work, we test the usage of three standardly positioned microphone probes. The aim is to compare two different approaches for enhancing the PCG signal quality, namely a) selecting the single source with the highest Signal-to-Noise Ratio (SNR) and b) combining the three sources through array signal processing techniques. Both approaches were tested on a sample population counting 24 healthy subjects. We found that the two approaches above give statistically different results (two-tailed paired t-test, p = 0.037) in terms of SNR of the enhanced signal. Specifically, selecting the single source with highest SNR gives, on average, the best results. Moreover, this approach is also associated with the lowest computational cost. Finally, for every subject of our sample population, we obtained SNR values higher than 12.5 dB on the enhanced signal, which we consider as sufficient for the application of heart sound segmentation and classification algorithms. We believe that this methodology allows for obtaining PCG signals of sufficient quality for the analysis of heart sounds, thus opening to the applicability of PCG in a homecare context.