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An Active Method for Tracking Connectivity in Temporally Changing Brain Networks

机译:用于跟踪脑网络中跨越脑网络的连接的主动方法

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The inference of connectivity in brain networks has typically been performed using passive measurements of ongoing activity across recording sites. Passive measures of connectivity are harder to interpret, however, in terms of causality - how evoked activity in one region might induce activity in another. To obviate this issue, recent work has proposed the use of active stimulation in conjunction with network estimation. By actively stimulating the network, more accurate information can be gleaned regarding evoked connectivity. The assumption in these previous works, however, was that the underlying networks were static and do not change in time. Such an assumption may be limiting in situations of clinical relevance, where the introduction of a drug or of brain pathology, might change the underlying networks structure. Here, an extension of the evoked connectivity paradigm is introduced that enables tracking networks that change in time.
机译:通常使用跨记录站点的持续活动的被动测量来执行脑网络中连接中的连接的推断。无源措施的连接措施更加难以解释,然而,在因果关系方面 - 如何在一个地区诱发活动可能会引起另一个区域的活动。为了避免这个问题,最近的工作提议结合网络估计使用积极刺激。通过积极刺激网络,可以针对诱发的连接收集更准确的信息。然而,在这些前面的作品中的假设是底层网络是静态的并且不会及时改变。这种假设可以限制临床相关性的情况,其中引入药物或脑病理学,可能会改变底层网络结构。这里,介绍了诱发连接范例的扩展,使得能够跟踪随时间变化的网络。

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