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Parameter exploration of staircase-shape extracellular stimulation for targeted stimulation of myelinated axon

机译:岩石型骨质刺激阶梯形状刺激的参数探索米盈轴突

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Spatio-temporal dynamics of a mathematical model of myelinated axon in response to staircase-shape extracellular electrical stimulation, which was developed for selective nerve stimulation, is investigated by the computer simulation. It is shown that the response is classified into four types: subthreshold response, cathodic excitation, anodal block and anodal break excitation. Based on the simulation results, simple diagrams representing the response characteristics of the axon are constructed as functions of stimulation parameters and distance between the axon and electrode. The diagram would be useful for determining simulation parameters for dynamic targeted stimulation of myelinated axon.
机译:通过计算机模拟研究了响应于阶梯形状的细胞外电刺激的凹部轴突的数学模型的时空动态,这是用于选择性神经刺激的阶梯形状的电刺激。结果表明,响应分为四种类型:亚阈值响应,阴极激励,anoOdal块和anodal断裂激发。基于仿真结果,表示轴突的响应特性的简单图被构造为刺激参数的功能和轴突和电极之间的距离。该图对于确定Myelized Axon的动态刺激的模拟参数是有用的。

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