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Modeling of lung's electrical impedance using fractional calculus for analysis of heat generation during RF-ablation

机译:使用分数演算对肺电阻抗建模以分析射频消融过程中的热量产生

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Recently, Radio Frequency Ablation (RFA) is becoming a popular therapy for various cancers such as liver, breast, or lung cancer. RFA is one kinds of thermal therapy. However, it has been often reported about excessive ablation or non-ablation due to difficult control of ablation energy. In order to solve these difficulties, we have been proposed robotized RF-ablation system for precise cancer treatment. We have been tried to control heat energy by control of electromagnetic-wave frequency. In this paper, we reported about relation among electrical impedance of lung, lung's internal air volumes, and heat energy by use of electromagnetic-wave. In case of RFA for lung cancer, heat energy depends on electrical impedance and lung's internal air volumes. Electrical impedance has the dependence of electromagnetic-wave frequency and the dependence of lung's internal air volumes. Therefore, firstly we considered about fractional calculus model between lung's internal air volumes and electrical impedance. Secondly, we measured electric impedance frequency characteristic of lung with change of lung's internal air volumes. The measured and modeled results showed that use of fractional calculus realized high accurate model for electrical impedance of lung. And, from the results of numerical analysis of heat energy, it is supposed that control of electromagnetic-wave frequency has a small effectiveness for lung tissue ablation even if lung includes abundant air.
机译:最近,射频消融(RFA)成为各种癌症(例如肝癌,乳腺癌或肺癌)的流行疗法。 RFA是一种热疗法。然而,由于难以控制消融能量,经常有关于过度消融或不消融的报道。为了解决这些困难,我们已经提出了用于精确癌症治疗的机器人射频消融系统。我们试图通过控制电磁波频率来控制热能。在本文中,我们通过电磁波报道了肺的电阻抗,肺的内部空气量和热能之间的关系。对于用于肺癌的RFA,热能取决于电阻抗和肺部内部空气量。电阻抗具有电磁波频率的依赖性和肺部内部空气量的依赖性。因此,首先,我们考虑了肺部内部空气量和电阻抗之间的分数演算模型。其次,我们测量了随着肺部内部空气量变化的肺部电阻抗频率特性。测量和建模结果表明,分数阶微积分的使用实现了肺电阻抗的高精度模型。并且,根据热能的数值分析结果,可以认为即使肺中包含大量的空气,电磁波频率的控制对肺组织消融的效果也较小。

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