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Creation of a Database Including a Set of Biological Features Related to Protein Sequences and Their Corresponding Alignment

机译:创建一个数据库,包括一组与蛋白质序列及其相应比对有关的生物学特征

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There are currently several biological databases related to proteins depending on the information we are interested to extract. Therefore, since a heterogeneous set of features will be needed (domains, structures, ontology terms, etc), several quite different databases should be consulted. The handling of different databases can become difficult, as each database could provide a different nomenclature for the same proteins. Anyway, these databases usually provides some mapping tools in order to determine the correspondence among the different nomenclatures used for the same protein. The main goal of this paper is to provide a biological database including a huge amount of protein information in order to be used for different purposes in bioinformatics. This database will be designed as a flexible and extensible tool and it could be extended and updated when new proteins are annotated or the included ones are modified.
机译:当前有几种与蛋白质有关的生物学数据库,具体取决于我们要提取的信息。因此,由于将需要一组异类的功能(域,结构,本体术语等),因此应查询几个完全不同的数据库。处理不同的数据库可能会变得困难,因为每个数据库可能为相同的蛋白质提供不同的命名法。无论如何,这些数据库通常提供一些映射工具,以便确定用于同一蛋白质的不同命名法之间的对应关系。本文的主要目的是提供一个包含大量蛋白质信息的生物学数据库,以便在生物信息学中用于不同目的。该数据库将被设计为一种灵活且可扩展的工具,当注释新蛋白质或修改其中包含的蛋白质时,可以对其进行扩展和更新。

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