A study for automatic diagnosing system of Parkinson Disease: A systematic analysis of Parkinsonian tremor by accelerometer

摘要

New objective diagnosing methods of Parkinson Disease is proposed with 3 D accelerometers. A mathematical model based on the peripheral feedback theory is tested by computer simulation with good coincident with the clinical data. We have found the main frequency of Parkinsonian tremor is about 4Hz in arms comparing the one of physiological tremor (8Hz). Patients in L-Dopa treatment have been measured by the system that corresponds well to a parameter Fgk that indicates the fatigue of intrafusal muscle. Biofeedback training by sound and visual parameters are also proved with good tremor improvement in its main frequency and severity.