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Discovering Relations between Indirectly Connected Biomedical Concepts

机译:发现间接联系的生物医学概念之间的关系

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The complexity and scale of the knowledge in the biomedical domain has motivated research work towards mining heterogeneous data from structured and unstructured knowledge bases. Towards this direction, it is necessary to combine facts in order to formulate hypotheses or draw conclusions about the domain concepts. In this work we attempt to address this problem by using indirect knowledge connecting two concepts in a graph to identify hidden relations between them. The graph represents concepts as vertices and relations as edges, stemming from structured (ontologies) and unstructured (text) data. In this graph we attempt to mine path patterns which potentially characterize a biomedical relation. For our experimental evaluation we focus on two frequent relations, namely "has target", and "may treat". Our results suggest that relation discovery using indirect knowledge is possible, with an AUC that can reach up to 0.8. Finally, analysis of the results indicates that the models can successfully learn expressive path patterns for the examined relations.
机译:生物医学领域知识的复杂性和规模促使研究工作从结构化和非结构化知识库中挖掘异构数据。朝着这个方向,有必要结合事实以便提出假设或得出关于领域概念的结论。在这项工作中,我们尝试通过使用间接知识将图形中的两个概念联系起来以识别它们之间的隐藏关系,从而解决该问题。该图表示来自结构化(本体)和非结构化(文本)数据的概念,其概念表示为顶点,关系表示为边缘。在此图中,我们尝试挖掘可能表征生物医学关系的路径模式。对于我们的实验评估,我们关注两个频繁的关系,即“有目标”和“可以治疗”。我们的结果表明,使用间接知识进行关系发现是可能的,并且AUC可以达到0.8。最后,对结果的分析表明,该模型可以成功地学习所检查关系的表达路径模式。

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