Inhalable Magnetic Nanocomposite Microparticles (MnMs) Dry Powders for Targeted Pulmonary Delivery

摘要

Inhalable dry powder nanocomposites consisting of MNPs and ACAs were successfully synthesized with advanced spray drying. Cytotoxicity studies show that cisplatin and erlotinib retain their activity with human lung cell lines, and heating studies show that MNPs released from SD powders can be remotely heated. These results illustrate the potential of these materials for inhalable lung cancer treatment modalities.