The roles ot the vitrification temperature, time and relative humidity in CV synthesis were investigated using a systematic DOE approach. Altering the synthesis parameters facilitated control and custom tailoring of the structure and therefore the transmittance, mechanical properties and thermal stability of the biomaterial. The DOE analysis showed that the most influential parameters for the transmittance and tensile strength are time and the interaction between time and temperature. In addition, the systematic DOE and analysis performed in this work enabled improvements of 113% in tensile strength and 11% in transmittance, compared to the previously developed CVs, and a 3-week reduction in synthesis time, rendering the vitrigels a more practical solution.
展开▼
