Effect of PGS-PCL Electrospun Fibers Orientation on Alignment and Proliferation of Human Umbilical Vein Endothelial Cells

摘要

We successfully fabricated aligned and random scaffolds from PGS and PCL. We investigated the effect of PGS-PCL fiber orientation on HUVECs alignment. HUVECs readily proliferate on aligned scaffolds and significantly higher orientation of cells was observed on the aligned scaffolds. With this, we can conclude that the fiber orientation plays a significant role in HUVECs alignment and proliferation and thus they can potentially be used for vascular tissue engineering.