Preparation of Micrcogels Using Thiol-Ene 'Click' Chemistry

摘要

We have successfully synthesized step-growth microgels using a visible-light mediated thiol-ene photo-click reaction. Comparison of reaction conditions revealed that mineral oil with Pluronic-F68 surfactant is a better synthesis method because it produced smaller, more uniform microgels without using toxic components. Adjusting mixing time, surfactant concentration, and macromer solution viscosity significantly affected the particle size. Ongoing work is focused on synthesizing multilayer microgels using interfacial thiol-ene photo-click reacionts.