Pro-angiogenic and Anti-inflammatory Biomaterial Therapies for Peripheral Artery Disease

摘要

This study suggests that combinatorial polymer scaffolds loaded with C16 and Ac-SDKP peptides can be considered as a promising therapeutic means for PAD. Despite the interdependency between the two types of host responses, pro-angiogenic and anti-inflammatory processes were activated through co-treatment of the peptides. On-going works utilize injectable scaffolds made from the combinatorial polymer library for a minimally invasive treatment of the peptide therapeutics.