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A method to quantitatively evaluate changes in tremor during deep brain stimulation surgery

机译:一种定量评估深部脑刺激手术中震颤变化的方法

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Deep Brain Stimulation (DBS) surgery is used increasingly as a symptomatic treatment for patients with movement related neuro-degenerative disorders. However, the method of intraoperative symptom evaluation is subjective. This paper proposes a method to quantitatively evaluate tremor by measuring the acceleration of the patient's wrist during the surgery. The results of applying the method to 2 patients suggest that the acceleration measurements are very sensitive to the change in the tremor and that they can be used to identify clinically effective stimulation amplitudes. By collecting acceleration data from DBS surgeries for many patients, we hope to add more knowledge to the mechanisms of deep brain stimulation.
机译:对于与运动有关的神经退行性疾病的患者,深部脑刺激(DBS)外科手术越来越被用作对症治疗。但是,术中症状评估的方法是主观的。本文提出了一种通过测量手术过程中患者手腕的加速度来定量评估震颤的方法。将这种方法应用于2位患者的结果表明,加速度测量值对震颤的变化非常敏感,因此可用于识别临床上有效的刺激幅度。通过收集来自许多患者的DBS手术的加速数据,我们希望为深部脑刺激的机制增加更多的知识。

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