Biolmage Computation

摘要

Biolmage Computing (BIC) is a rapidly growing field at the interface of computer vision and the life sciences. Advanced light microscopy can deliver 2D and 3D image sequences of living cells with unprecedented image quality and ever increasing resolution in space and time. The emergence of novel and diverse microscopy modalities has provided biologists with unprecedented means to explore cellular mechanisms, embryogenesis, or neural development, to mention only a few areas of research. Electron microscopy provides information on the cellular structure at nanometer resolution. Here, correlating light microscopy and electron microscopy at the subcellular level, and relating both to animal behavior at the macroscopic level, is of paramount importance. The enormous size and complexity of these data sets, which can exceed multiple TB per volume or video, requires not just accurate, but also efficient computer vision methods.