Fabrication and Characterization of Novel Hydroxyapatite/Porous Carbon Composite Scaffolds

摘要

Novel Hydroxyapatite (HA)/porous carbon composite scaffolds were prepared by combining sonoelectrodeposition and the hydrothermal treatment method. The interconnected pore network and morphology of HA/porous carbon composite scaffolds were determined by scanning electron microscope (SEM), and the whole surface of porous carbons were evenly coated with the deposited HA layer which was confirmed by EDS and XRD. The porosity (83.50.3%) and the bulk density (0.2970.009gcm-3) of HA/porous carbon scaffolds were detected by the Archimedes method. The compressive and flexural strength of the scaffolds is 1.1870.064MPa and 0.6070.268MPa, respectively. Compared with the 24-well cell culture plate, these novel scaffolds significantly promote the proliferation of human osteoblast-like MG-63 cells, indicating that this novel HA/porous carbon composite scaffold could be used for in vitro 3D culture of osteoblasts.