The In Vitro Micro-environment Interface: Macromolecular Crowding Meets Cell-Sheet Tissue Engineering

摘要

Modulation of the in vitro microenvironment with macromolecular crowding not only maintains cell viability but also enhances extracellular matrix deposition even under low serum/ HS supplementation. NIPAM based co-polymers supports complete detachment of cell-matrix-rich sheet.