MODULATION OF CYTOCHROME P450 ENZYME FUNCTION AND EXPRESSION BY PIPERINE IN CELLULOSIC SPONGE SYSTEM

摘要

Piperine proves to be a potent inducer for cypla2, 2b2 and 3a2 in rat hepatocytes which implies possible food-drag interaction with the co-administration of drugs that are CYP1A, 2B and 3A substrates.