The Impact Of Lighting On Eye Refractive Development

摘要

To investigate effects of color vision on eye refractive development and its mechanisms.In comparison with those raised in white light or blue light,monkeys raised in red light showed significant myopic shift in refraction (approximately 3D,p＜0.001) associate with longer vitreous chamber by the end of treatment,which was well beyond the estimated chromatic defocus between 455nm and 610nm (approximately 1D).Long wavelength light appeared to interfere with emmetropization process and produce more myopic shift than white light dose.The results indicated that accommodation model under monochromatic light and L/M opponent mechanism might play a role in regulating eye growth in addition to chromatic defocus.To investigate the refrective development and levels of Dopamine in guinea pigs under the conditions of varied light intensity(5Lux,500Lux,10000Lux,white light,colour temperatura 6000K)and the possible mechanism.High light intensity can slow the growth of the axial length and emmetropization process in guinea pigs,while low light intensity makes no differance to the normal eye development of the guinea pigs.The levels of Dopamine can be increased on the condition of high light intensity,which may partly explain the change of the eye development.High light intensity may cause slight injury to the retina photoreceptors of guinea pigs.