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A data-driven process for the development of an eyes-closed EEG normative database

机译:闭眼式EEG规范数据库开发的数据驱动过程

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A normative database constitutes a representative sample of a neurologically and clinically healthy population. The practical utility of a normative EEG database is to evaluate the clinical status of a subject whose EEG patterns statistically diverge from average population patterns. These normative data are daily used in clinical practice and in the evaluation of therapeutical interventions. The main obstacle of all normative databases developed to date is inter-individual variability. Such difficulty has been addressed by stratifying the population by age and then using regression in the EEG groups to bound variability, which is always an approximation. This paper describes the first data-driven EEG normative database that explicitly deals with EEG variability by stratifying the population based on their EEG patterns. The database has been constructed for 84 subjects in eyes-closed condition and has been validated by cross validation, leading to a global specificity of 100%.
机译:规范数据库构成了神经和临床健康人群的代表性样本。规范性EEG数据库的实际用途是评估其EEG模式在统计学上与平均人群模式不同的受试者的临床状况。这些规范性数据每天都用于临床实践和评估治疗干预措施。迄今为止开发的所有规范数据库的主要障碍是个体间的可变性。通过按年龄分层总体,然后在EEG组中使用回归来约束可变性(始终是一个近似值),可以解决这种困难。本文介绍了第一个数据驱动的脑电图规范数据库,该数据库通过根据其脑电图模式对人群进行分层来明确处理脑电图变异性。该数据库针对84位闭眼受试者进行了构建,并通过交叉验证进行了验证,全球特异性为100%。

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