Automatic EEG spike detection provide valuable information for diagnosis of epilepsy. In the past 30 years, a number of algorithms were proposed. However, the basic idea of most algorithms is to identify spike activities. We have developed an algorithm based on identify non-spike activities for off-line analysis. In this paper, we improved the algorithm for online application using real-time template. Template method is a typical spike detection method. It was not widely employed because of the difficulty of making template. Our results suggested that multi-channel template is meaningful and effective for real-time detection. Spike activities can be detected with a delay of about 2 s. We also designed an simple user-friendly monitor interface for monitor and review spike events in real-time.
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