Fibrin targeted block copolymers demonstrated the ability to suppress fibrin deposition and cellular adhesion. A complex relationship between material properties and performance was identified, providing insights into the further development. A single infusion of a blocking polymer was able to reduce the degree of observed adhesions at sites of peritoneal injury but not at synthetic sites (e.g., adhesions to the suture knot), suggesting the potential use of targeted polymers as post-surgical adhesion suppressing agents.
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