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Multi-Diffusion-Tensor Fitting via Spherical Deconvolution: A Unifying Framework

机译:通过球面反卷积的多扩散张量拟合:一个统一的框架

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In analyzing diffusion magnetic resonance imaging, multi-tensor models address the limitations of the single diffusion tensor in situations of partial voluming and fiber crossings. However, selection of a suitable number of fibers and numerical difficulties in model fitting have limited their practical use. This paper addresses both problems by making spherical deconvolution part of the fitting process: We demonstrate that with an appropriate kernel, the deconvolution provides a reliable approximative fit that is efficiently refined by a subsequent descent-type optimization. Moreover, deciding on the number of fibers based on the orientation distribution function produces favorable results when compared to the traditional F-Test. Our work demonstrates the benefits of unifying previously divergent lines of work in diffusion image analysis.
机译:在分析扩散磁共振成像时,多张量模型解决了部分体积和纤维交叉情况下单个扩散张量的局限性。但是,选择合适数量的纤维以及模型拟合中的数值困难限制了它们的实际应用。本文通过使球形反褶积成为拟合过程的一部分来解决这两个问题:我们证明,通过适当的核,反褶积提供了可靠的近似拟合,可以通过后续的下降类型优化对其进行有效地细化。此外,与传统的F检验相比,基于取向分布函数确定纤维数量会产生良好的结果。我们的工作证明了在扩散图像分析中统一以前不同的工作线的好处。

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