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Fast Integration Treatment (FIT), a New Nanostructured Titanium Carbide Based Film, that Reduces more than 50 the Osseointegration Time of Surgical Implants

机译:快速整合治疗(FIT),一种新型的纳米结构碳化钛基薄膜,可减少手术植入物的骨整合时间的50%以上

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The use of titanium surgical prosthesis for dental and orthopaedic implants is continuously growing, mainly because the aging of the population of industrial ized countries. A drawback of these surgical operations resides in the long period necessary to reach a complete osseointegration and, than, to charge the prosthesis. This paper describes the biological results obtained with a new treatments (patent pending) realized by Pulsed Laser Ablation Deposition PLAD and Ion Plating Plasma Assisted IPPA vacuum deposition, evaluated both "in vitro" and "in vivo" and the compositional characteristics of the deposited nanostructured film. The tests performed, also with real dental prosthesis, implanted into rabbit legs, show an improvement in the osseointegration activity that induces to expect a reduction better than 50% in the "time to charge" in human bones. The treatment acts also as protection of the titanium prosthesis from the aggressive attacks of biological fluids and tissues;The IPPA treatment represents an evolution of a previous one, based on Pulsed Laser Ablation Deposition, that is not suitable for a real industrial production on 3D shaped substrates. Some details of the IPPA deposition process and the methods of biological characterizations are also reported.
机译:钛外科假体在牙科和整形外科植入物中的使用正在不断增长,这主要是由于工业化国家人口的老龄化。这些外科手术的缺点在于,需要长时间才能达到完整的骨整合,而不是对假体进行充电。本文介绍了通过脉冲激光烧蚀沉积PLAD和离子镀等离子体辅助IPPA真空沉积实现的新治疗方法(正在申请专利)获得的生物学结果,评估了“体外”和“体内”以及沉积纳米结构的组成特征电影。所进行的测试,也用真实的牙齿假体植入兔子腿中,显示出骨整合活性的改善,有望使人体骨骼的“充电时间”减少超过50%。这种治疗还可以保护钛假体免受生物体液和组织的侵蚀。 IPPA处理代表了基于脉冲激光烧蚀沉积技术的前一种技术的发展,该技术不适合在3D形状的基板上进行实际的工业生产。还报告了IPPA沉积过程的一些细节以及生物学特性的方法。

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