Simulated Moving Bed Modeling and Application

摘要

Simulated moving bed (SMB) technology as an increasingly used chromatographic separation and preparation technique is reported in this paper.The principle,model,new development,optimization of SMB and major applications of SMB chromatography (SMBC) technology for separation are also reviewed.In addition,a new model solving method,the space-time conservation element and solution element (so-called CE/SE),is also discussed in a brief introduction.Applying the CE/SE method for SMB chromatographic problems,accurate solutions can be obtained and fast calculation can be achieved,respectively.