Sustained intracellular Concentrations of Mometasone furoate Upon Administration in WGA-conjugated PLGA nanoparticles

机译：WGA偶联的PLGA纳米颗粒中施用后糠酸莫米松的持续细胞内浓度

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摘要

Mometasone furoate (MF) encapsulated, Wheat germ agglutinin (WGA) conjugated, poly(D,L-lactic-co-glycolic) acid (PLGA) nanoparticles were prepared and characterized. These nanoparticles were studied for their in-vitro antiproliferative activity and sustained intracellular drug concentrations on A549 cells.

机译：制备了糠酸莫米松（MF），共轭小麦胚芽凝集素（WGA），聚（D，L-乳酸-乙醇酸）（PLGA）纳米颗粒，并对其进行了表征。研究了这些纳米颗粒的体外抗增殖活性以及在A549细胞上持续的细胞内药物浓度。

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《Controlled Release Society Annual Meeting and Exposition》|2007年|P.650-651|共2页
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Naazneen Surti; Sachin Naik; T. Bagchi; B.S. Dwarkanath; Ambikanandan Misra;
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中图分类生物工程学（生物技术）;
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1. Comparison of the systemic bioavailability of mometasone furoate after oral inhalation from a mometasone furoate/formoterol fumarate metered-dose inhaler versus a mometasone furoate dry-powder inhaler in patients with chronic obstructive pulmonary disease [J] . Teddy Kosoglou, James Hubbell, Fengjuan Xuan, International Journal of Chronic Obstructive Pulmonary Disease . 2013,第1s期

机译：慢性阻塞性肺疾病患者口服糠酸莫米松/福莫特罗富马酸盐计量吸入器与糠酸莫米松干粉吸入器口服吸入后，糠酸莫米松的全身生物利用度比较
2. Serious asthma events with mometasone furoate plus formoterol compared with mometasone furoate [J] . Weinstein Cindy L. J., Ryan Nicholas, Shekar Tulin, The Journal of Allergy and Clinical Immunology . 2019,第4期

机译：与Mometasone Furoate Plus Formoterol的严重哮喘活动与米多塞氏菌相比
3. EFFICACY AND SAFETY OF MOMETASONE FUROATE/FORMOTEROL COMPARED WITH MOMETASONE FUROATE IN CHILDREN WITH PERSISTENT ASTHMA [J] . Weinstein C., Gates D., Zhang X., Annals of allergy, asthma, and immunology . 2019,第5Suppla1期

机译：与持续性哮喘持续存在的儿童的莫替塞酮呋喃酸酯相比，米多酮呋喃酸盐/蛋白质的疗效和安全性
4. Sustained intracellular Concentrations of Mometasone furoate Upon Administration in WGA-conjugated PLGA nanoparticles [C] . Naazneen Surti, Sachin Naik, T. Bagchi, Controlled Release Society Annual Meeting and Exposition . 2007

机译：在WGA缀合的PLGA纳米粒子施用时，持续的米多塞氏菌的细胞内浓度
5. An analysis of the interaction and intracellular fate of nanoparticles in epithelial cells: Application in oral delivery of PLGA nanoparticles encapsulating curcumin for treatment of cystic fibrosis [D] . Cartiera, Malgorzata Sylvia 2007

机译：纳米粒子在上皮细胞中的相互作用和细胞内命运的分析：包裹姜黄素的PLGA纳米粒子在口服中的应用在治疗囊性纤维化中的应用
6. Comparison of the systemic bioavailability of mometasone furoate after oral inhalation from a mometasone furoate/formoterol fumarate metered-dose inhaler versus a mometasone furoate dry-powder inhaler in patients with chronic obstructive pulmonary disease [O] . Teddy Kosoglou, James Hubbell, Fengjuan Xuan, 2013

机译：慢性阻塞性肺疾病患者口服糠酸莫米松/福莫特罗富马酸盐计量吸入器与糠酸莫米松干粉吸入器口服吸入后糠酸莫米松的全身生物利用度比较
7. Medium-Dose Indacaterol/Glycopyrronium/Mometasone Furoate Fixed-Dose Combination Improves Lung Function Compared with High-Dose Indacaterol/Mometasone Furoate and Salmeterol/Fluticasone and Reduces Exacerbation Rates Versus High-Dose Salmeterol/Fluticasone in Moderate-to-Severe Asthma: The IRIDIUM Study [O] . A. Papi, M. Humbert, K. Kostikas, 2020

机译：中剂量茚钒/甘油酮/米多酮呋喃固定剂组合改善了肺功能与高剂量茚钒/米多酮呋喃（Salmeterol / Fluticason）相比，并降低了中度至严重的哮喘中的高剂量Salmeterol /氟替卡松的恶化率：铱学习

Sustained intracellular Concentrations of Mometasone furoate Upon Administration in WGA-conjugated PLGA nanoparticles

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